One of the main challenges to treat chronic pain is an absence of objective ways to quantify pain. Self-pain report is a reliable but simplistic measure of the 

complex pain experience and it does not inform about brain mechanisms and pathophysiology of pain. We propose a wearable system, named Painometry, which objectively quantifies user’s pain perception based on multiple physiological and neural signals, including novel sweep impedance profiling (SIP) sensor, developed by our group. Painometry, a multimodality sensing system, can accurately quantify 3 levels of pain with 89% accuracy.