Welcome to the Integrative Pain Laboratory!
We are aiming to gain a deeper understanding of chronic pain conditions to develop
new ways of measuring, preventing, and treating chronic pain. 

We are supporting chronic pain patients and medical specialists in learning and integrating the new knowledge about chronic pain for boosting the healing process.

PAIN Journal – New Publication 

One of the pleasant surprises at IASP 2024 was seeing the latest issue of PAIN Journal with our research featured on the cover. Our paper, “Defining Suffering in Pain: A Systematic Review Using Natural Language Processing,” focuses on the complexity of pain-related suffering.
In this study, we identified eight key dimensions and developed a new conceptual framework, combining a systematic review with advanced machine learning techniques. We hope this contribution will enhance the understanding of pain and suffering in both clinical and research settings. Read full article>>

Epoch Magazine featuring Pavel Goldstein 

In a thought-provoking article, Pavel Goldstein provides insights into the opioid crisis in Israel and outlines potential preventive measures. “It’s imperative that we take proactive steps to address this issue and avoid the tragic consequences witnessed in the USA”. Read full article>>

Publications

Understanding and dealing with pain-related suffering is a big challenge in healthcare and research. But there’s no agreement on exactly what it means, and it’s often not clearly defined in studies. Here, we did three things: (1) looked at how pain-related suffering is understood in existing research, (2) made our own definition and framework, and (3) checked our results using machine learning. We found 111 articles in our search and used a new method to analyze them. From this, we defined pain-related suffering as a very negative, complex experience when someone feels their well-being is threatened. We also created a framework with 8 dimensions to understand it better: social, physical, personal, spiritual, existential, cultural, cognitive, and affective. Our findings show that pain-related suffering is different from but closely connected to pain itself. This analysis gives direction for more research in this area. Read full artice>>

The mechanisms that underlie social touch analgesia are largely unknown. Here, we apply a hyperscanning approach with real-life interaction of dyads to examine the association between brain-to-brain coupling and pain relief. Our findings indicate that hand-holding during pain increases the brain-to-brain coupling network that correlates with the magnitude of the analgesia and the observer’s empathic accuracy. These findings make a unique contribution to our understanding of the physiological mechanisms of touch-related analgesia. Read full artice>> 

We developed a mobile platform for measuring pain, emotions, and associated bodily feelings in chronic pain patients in their daily life conditions. We developed predictive models of future pain based on the interactive effects of (a) body maps of fatigue with negative affect and (b) positive affect with past pain. Read full article>>

In the media:

Mako (10.02.2021): רוצים לסבול פחות מכאבים כרוניים? תנוחו יותר ותשליכו רגשות שליליים